About Sevanier 400 Tablet
Sevanier 400 Tablet is used to treat increased phosphate levels in the blood. It is used in patients who are on dialysis due to severe kidney disease. It inhibits the absorption of phosphate from the intestine and lowers the phosphate levels in the blood. Sevanier 400 Tablet should be taken with food. Take it in the dose and duration as advised by your doctor. Take it regularly and at a fixed time each day to get the maximum benefit of the medicine. Sevanier 400 Tablet may cause side effects such as nausea, vomiting, abdominal pain, constipation, and diarrhea. You may also develop low levels of calcium, folic acid, and vitamins A, D, E, and K in your blood. Take necessary supplements as advised by your doctor.
Uses of Sevanier 400 Tablet
- High phosphate levels in blood
How to use Sevanier 400 Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sevanier 400 Tablet should be taken with or after food.
How Sevanier 400 Tablet works
Sevanier 400 Tablet inhibits the absorption of phosphate from the intestine and lower the phosphate levels in the blood.
Side effects of Sevanier 400 Tablet
Most side effects do not need medical attention and go away as your body adjusts. Talk to your doctor if they persist or worry you. Common side effects include:
- Abdominal pain
- Diarrhea
- Flatulence
- Nausea
- Vomiting
- Constipation
If you miss a dose
If you miss a dose of Sevanier 400 Tablet, skip it and continue with your normal schedule. Do not double the dose.
Storage
Store below 30°C. Keep out of the reach of children. How to store medicines at home.
Interactions with other medicines
Tell your doctor about every medicine you take. Known interactions include:
- Ofloxacin (Oral Route): Moderate To take Ofloxacin, ensure a gap of at least 1 hour before and 3 hours after taking Sevelamer. Sevelamer may reduce blood levels of Ofloxacin.
- Sparfloxacin (Oral Route): Moderate To take Sparfloxacin, ensure a gap of at least 1 hour before and 3 hours after taking Sevelamer. Sevelamer may reduce blood levels of Sparfloxacin.
- Norfloxacin (Oral Route): Moderate To take Norfloxacin, ensure a gap of at least 1 hour before and 3 hours after taking Sevelamer. Sevelamer may reduce blood levels of Norfloxacin.
- Levofloxacin (Oral Route): Moderate To take Levofloxacin, ensure a gap of at least 1 hour before and 3 hours after taking Sevelamer. Sevelamer may reduce blood levels of Levofloxacin.
Safety advice
It is not known whether it is safe to consume alcohol with Sevanier 400 Tablet. Please consult your doctor.
Sevanier 400 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Sevanier 400 Tablet does not usually affect your ability to drive.
There is limited data available on the use of Sevanier 400 Tablet in patients with kidney disease. Please consult your doctor.
Sevanier 400 Tablet is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.
Frequently asked questions
Is Sevanier 400 Tablet taken with food?
Yes, Sevanier 400 Tablet can be taken with food. It is recommended to take 1-2 tablets (based on individual needs) thrice daily. It is important to take it with meals because Sevanier 400 Tablet works by binding to phosphate from food. Take it exactly as advised by your doctor.
Can Sevanier 400 Tablet be crushed?
No, you should not crush, chew, or break Sevanier 400 Tablet into pieces. You should swallow it as a whole with water.
Why is it important for me to take Sevanier 400 Tablet?
It is important to take Sevanier 400 Tablet as patients undergoing dialysis cannot control the phosphate levels in their blood, especially after a meal. When the level of phosphate exceeds above the range in the blood, it may cause problems such as itchy skin, red eyes, high blood pressure, bone pain, and also increase the risk of fractures. These increased serum phosphate levels are reduced by Sevanier 400 Tablet, as it binds phosphate from food in the digestive tract.
Does Sevanier 400 Tablet cause constipation?
A common side effect of Sevanier 400 Tablet is constipation, though it does not occur in everyone. The other common side effects of the stomach and intestine include diarrhea, indigestion, flatulence, and pain in the abdomen. Immediately consult your doctor if these side effects become severe and disturb you.
Who should not take Sevanier 400 Tablet?
Patients who are allergic to Sevanier 400 Tablet and who have low levels of phosphate in blood should avoid taking Sevanier 400 Tablet. Additionally, patients having intestinal obstruction should also avoid using Sevanier 400 Tablet.
Can I take ciprofloxacin while I am taking Sevanier 400 Tablet?
Ciprofloxacin may interfere with the working of Sevanier 400 Tablet and therefore it should not be taken at the same time as Sevanier 400 Tablet. However, if taken together then a gap of at least 2 hours before or 6 hours after taking Sevanier 400 Tablet should be maintained.
This information is for reference only and does not replace advice from your doctor or pharmacist. Do not start, stop or change a medicine without medical advice. Details come from the product’s listing and may differ from the pack you receive; always read the label.


