About Carbenz 450 Injection
Carbenz 450 Injection is used in the treatment of ovarian cancer and small cell lung cancer. It shows its working by stopping or slowing down the growth of cancer cells. Carbenz 450 Injection is given as an injection into veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Nausea, vomiting, fatigue, and increased liver enzyme are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Inform your doctor if you notice fever, sore throat, chills, unusual bleeding or bruising, and dark urine. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels. You must inform your doctor if you experience allergic reactions with injection such as skin rash, itching, and trouble breathing. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Carbenz 450 Injection
- Ovarian cancer
- Small cell lung cancer
Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Carbenz 450 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but has some side effects that may be bothersome. So, you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
How to use Carbenz 450 Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Carbenz 450 Injection works
Carbenz 450 Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication.
Side effects of Carbenz 450 Injection
Most side effects do not need medical attention and go away as your body adjusts. Talk to your doctor if they persist or worry you. Common side effects include:
- Nausea
- Vomiting
- Anemia (low number of red blood cells)
- Fatigue
- Low blood platelets
- Increased liver enzymes
- Decreased white blood cell count (neutrophils)
- Stomatitis (Inflammation of the mouth)
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Diarrhea
If you miss a dose
If you miss a dose of Carbenz 450 Injection, please consult your doctor.
Storage
Store below 25°C. Keep out of the reach of children. How to store medicines at home.
Interactions with other medicines
Tell your doctor about every medicine you take. Known interactions include:
- Pegfilgrastim (Injection Route): Life-threatening Do not consume Carboplatin from 14 days before until 24 days after taking Pegfilgrastim. Please consult your doctor. Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
- Sargramostim (Injection Route): Life-threatening Do not consume Carboplatin from 1 day before until 1 day after taking Sargramostim. Please consult your doctor. Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
- Lenograstim (Injection Route): Life-threatening Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytotoxic chemotherapy. Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
- Molgramostim (Injection Route): Life-threatening Do not consume Carboplatin from 1 day before until 1 day after taking Molgramostim. Please consult your doctor. Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Safety advice
Do not drink alcohol while you are taking this medicine. Carbenz 450 Injection may cause excessive drowsiness when taken with alcohol.
Carbenz 450 Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Carbenz 450 Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Carbenz 450 Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed. Use of Carbenz 450 Injection is not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests may be advised while you are taking this medicine.
Carbenz 450 Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.
Frequently asked questions
Is Carbenz 450 Injection cell cycle specific?
No, Carbenz 450 Injection is not a cell cycle specific anticancer medication
Is Carbenz 450 Injection FDA approved?
Yes Carbenz 450 Injection is an FDA approved drug
Is it a platinum based drug?
Yes carboplatin is a platinum based drug and is effectively used in combination with other drug
Does Carbenz 450 Injection cause neuropathy/ hearing loss/ hair loss/ weight gain/ constipation/ leukemia?
Yes Carbenz 450 Injection is known to cause side effects like neuropathy, hearing loss, hair loss, weight gain, and constipation. Please inform your doctor about any side-effect that you may observe on taking this drug. Infertility while on therapy may be caused as a side effect of this drug but it may be reverse after stopping the therapy. Yes Carbenz 450 Injection may cause leukemia if it is used for a long duration.
Is Carbenz 450 Injection a generic?
Yes, Carbenz 450 Injection is a generic platinum-based compound
Is Carbenz 450 Injection vesicant/cardio-toxic/ anthracycline?
No Carbenz 450 Injection is not cardio-toxic/ anthracycline/vesicant
This information is for reference only and does not replace advice from your doctor or pharmacist. Do not start, stop or change a medicine without medical advice. Details come from the product’s listing and may differ from the pack you receive; always read the label.
