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Glyoka-M1 Forte Tablet PR pack
Rx · Prescription requiredDiabetes Care

Glyoka-M1 Forte Tablet PR

Glimepiride (1mg) + Metformin (1000mg)

By Ayati Pharma Pvt Ltd · strip of 10 Tablet pr

Used for type 2 diabetes mellitus

MRP (incl. of all taxes)₹65.63

As listed on 4 October 2026. Always check the MRP printed on the pack; no pharmacy may charge more.

Prescription medicine. It is dispensed only by a licensed pharmacy against a valid prescription from a registered doctor, after a pharmacist checks it.

When MedMate launches, medicines are sold and dispensed by licensed partner pharmacies. The pharmacy’s name, address, drug licence number and pharmacist will be shown before you pay and on your invoice.

About Glyoka-M1 Forte Tablet PR

Glyoka-M1 Forte Tablet PR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes. Glyoka-M1 Forte Tablet PR should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you, and this may change from time to time according to how it is working, according to your blood sugar levels. Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes. The most common side effect of Glyoka-M1 Forte Tablet PR is low blood glucose levels (hypoglycemia). Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking, and know how to deal with them. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose, such as sugary food or fruit juice, with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Other side effects that may be seen on taking this medicine include taste changes, nausea, diarrhea, stomach pain, headache, and upper respiratory tract infection. Some people may find that they put on weight with this medicine. You should not take it if you have type 1 diabetes mellitus, diabetic ketoacidosis (high levels of acid in your blood), or severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly, and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

Uses of Glyoka-M1 Forte Tablet PR

  • Treatment of Type 2 diabetes mellitus

Glyoka-M1 Forte Tablet PR is a combination medicine that increases the amount of insulin your body produces (in the pancreas). The insulin then works to lower your blood glucose level. It is usually taken once a day. You should keep taking it for as long as it is prescribed. Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

How to use Glyoka-M1 Forte Tablet PR

Use it as advised by your doctor or check the label for directions before use. Glyoka-M1 Forte Tablet PR should be taken with or after food.

How Glyoka-M1 Forte Tablet PR works

Glyoka-M1 Forte Tablet PR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea that works by increasing the amount of insulin released by the pancreas to lower the blood glucose. Metformin is a biguanide that works by lowering glucose production in the liver, delaying glucose absorption from the intestines, and increasing the body's sensitivity to insulin.

Side effects of Glyoka-M1 Forte Tablet PR

Most side effects do not need medical attention and go away as your body adjusts. Talk to your doctor if they persist or worry you. Common side effects include:

  • Headache
  • Hypoglycemia (low blood glucose level)
  • Nausea
  • Diarrhea

If you miss a dose

If you miss a dose of Glyoka-M1 Forte Tablet PR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Storage

Store below 30°C. Keep out of the reach of children. How to store medicines at home.

Safety advice

AlcoholUnsafe

It is unsafe to consume alcohol with Glyoka-M1 Forte Tablet PR

PregnancyConsult your doctor

Glyoka-M1 Forte Tablet PR is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

BreastfeedingConsult your doctor
DrivingCaution

Glyoka-M1 Forte Tablet PR may affect your driving ability if your blood sugar becomes too low or too high. Monitor your blood glucose and avoid driving if affected.

KidneyUnsafe

Glyoka-M1 Forte Tablet PR is unsafe to use in patients with kidney disease and should be avoided. Use of Glyoka-M1 Forte Tablet PR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests is advisable while you are taking this medicine.

LiverUnsafe

Glyoka-M1 Forte Tablet PR is unsafe to use in patients with liver disease and should be avoided. Glyoka-M1 Forte Tablet PR is generally started with a low dose in patients with mild to moderate liver disease, and its use is not recommended in patients with severe liver disease.

Frequently asked questions

What is Glyoka-M1 Forte Tablet PR?

Glyoka-M1 Forte Tablet PR is a combination of two medicines: glimepiride and metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with a proper diet and regular exercise. Glimepiride lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.

Can the use of Glyoka-M1 Forte Tablet PR lead to lactic acidosis?

Yes, the use of Glyoka-M1 Forte Tablet PR can lead to lactic acidosis. It is a medical emergency that is caused by increased levels of lactic acid in the blood. It is also known as MALA (metformin-associated lactic acidosis). It is a rare side effect associated with the use of metformin, and therefore, it is considered to be harmful for patients with underlying kidney disease, older patients, or those who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, a feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain, or a slow heart rate. If you have these symptoms, stop taking Glyoka-M1 Forte Tablet PR and consult your doctor immediately.

What are the possible side effects of Glyoka-M1 Forte Tablet PR?

The use of Glyoka-M1 Forte Tablet PR is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, and headache. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.

Can the use of Glyoka-M1 Forte Tablet PR lead to Vitamin B12 deficiency?

Yes, the use of Glyoka-M1 Forte Tablet PR can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can experience tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.

Can the use of Glyoka-M1 Forte Tablet PR cause hypoglycemia?

Yes, the use of Glyoka-M1 Forte Tablet PR can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise, or take other antidiabetic medicines along with it. So, regular monitoring of the blood sugar level is important. Always keep a quick source of sugar, like glucose tablets, honey, or fruit juice, with you.

Is it safe to take alcohol while I am also taking Glyoka-M1 Forte Tablet PR?

No, it is not safe to take Glyoka-M1 Forte Tablet PR along with alcohol, as it may lower your blood sugar levels and lead to hypoglycemia. It can also increase the chances of lactic acidosis.

This information is for reference only and does not replace advice from your doctor or pharmacist. Do not start, stop or change a medicine without medical advice. Details come from the product’s listing and may differ from the pack you receive; always read the label.

Product details

Composition (generic name)
Glimepiride (1mg) + Metformin (1000mg)
Form
Tablet PR
Net quantity
strip of 10 Tablet pr
Prescription
Required
Marketed by
Ayati Pharma Pvt Ltd
Marketer’s address
B-313, 3rd Floor, Plot-616, B/3, Swarjya CH, Senapati Bapat marg, Dadar(W), Mumbai, Maharashtra 400002
Country of origin
India
MRP
₹65.63 (incl. of all taxes), as listed on 4 October 2026
Consumer care
As printed on the pack by the manufacturer or marketer
Habit Forming
No
Therapeutic Class
Anti diabetic

Same composition alternatives

These contain Glimepiride (1mg) + Metformin (1000mg). A pharmacist can offer a same-salt alternative only with your consent; ask your doctor if you are unsure. What “same salt” means

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