About Denbri Injection
Denbri Injection is a medicine used in the treatment of osteoporosis in postmenopausal women and in men at increased risk of fractures. It makes the bones strong and reduce the risk of fractures. Denbri Injection is given by a healthcare professional and should not be self-administered. You should use it regularly and at the same time each day to get maximum benefit from it. Continue using it as recommended by your doctor and complete the dose even if you feel better. To make it more effective, take adequate amount of calcium and vitamin D supplements while on treatment with this medicine. Some common side effects of this medicine include headache, pain in extremity, musculoskeletal pain, nerve pain, constipation, and rash. Talk to your doctor if any of these side effects does not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms. To make sure the medicine is safe for you, before taking it, let your doctor know of all the other medicines you are taking. It is important for pregnant and breastfeeding mothers to ask the advice of their doctors before using this medicine.
Uses of Denbri Injection
- Osteoporosis
How to use Denbri Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Denbri Injection works
Denbri Injection is a monoclonal antibody. It binds to a protein that causes bone loss, thereby strengthening the bone and minimizing the risk of fractures.
Side effects of Denbri Injection
Most side effects do not need medical attention and go away as your body adjusts. Talk to your doctor if they persist or worry you. Common side effects include:
- Rash
- Musculoskeletal (bone, muscle or joint) pain
- Eczema
- Upper respiratory tract infection
- Sciatica
- Pain in extremities
- Back pain
- Joint pain
- Urinary tract infection
- Constipation
- Abdominal discomfort
- Hair loss
- Hypercholesterolemia (high cholesterol)
- Cystitis
- Nerve pain
- Headache
If you miss a dose
If you miss a dose of Denbri Injection, please consult your doctor.
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.. Keep out of the reach of children. How to store medicines at home.
Interactions with other medicines
Tell your doctor about every medicine you take. Known interactions include:
- Cinacalcet (Oral Route): Moderate Your doctor may monitor your treatment and adjust the doses as per the observations. Denosumab may increase the metabolism of Cinacalcet.
Safety advice
It is not known whether it is safe to consume alcohol with Denbri Injection. Please consult your doctor.
Denbri Injection is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
It is not known whether Denbri Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Denbri Injection is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Denbri Injection is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.
Frequently asked questions
How long can you stay on Denbri Injection?
There is no optimal duration of treatment of osteoporosis with Denbri Injection. The patient’s response and tolerability to the medicine is continuously monitored through periodic assessments, especially after 5 years of use of Denbri Injection. Depending on this, the duration of taking Denbri Injection is decided.
Does Denbri Injection cause hair loss?
Yes, hair loss is a common side effect of Denbri Injection though it does not affect everyone. Discuss with your doctor if you have concerns regarding your hair loss.
Is Denbri Injection a chemotherapy drug?
Denbri Injection is not a chemotherapy drug. It is a protein (monoclonal antibody) that interferes with the action of another protein in order to treat bone loss and osteoporosis. Treatment with Denbri Injection makes the bones stronger and less likely to break.
How is Denbri Injection given and how often?
Denbri Injection is available as an injection and is given by a healthcare professional. It is given once in 6 months. Your doctor may also advise you to take calcium and vitamin D while taking Denbri Injection.
Can Denbri Injection be taken during pregnancy?
No, pregnant women should not take Denbri Injection. You must use an effective method of birth control during and for at least 5 months after the last dose of Denbri Injection if you can become pregnant.
How should Denbri Injection be stored?
Denbri Injection should be stored in a refrigerator at 36°F to 46°F (2°C to 8°C) in the original carton. Warm temperatures can make it ineffective, and therefore proper storage is necessary. When you remove it from the refrigerator, keep it at room temperature [up to 77°F (25°C)] in the original carton and use it within 14 days.
This information is for reference only and does not replace advice from your doctor or pharmacist. Do not start, stop or change a medicine without medical advice. Details come from the product’s listing and may differ from the pack you receive; always read the label.
